Our Services

Our mission at BioMetas is to provide our global clients with state of the art and innovative drug products, drug discovery, and development services.

Small Molecule Drug Discovery Solutions

• CRISPR Library Screen

• siRNA Gene KD

• shRNA Gene KD

• CRISPR/Cas9 Gene KO

• CRISPR/dCas9 Gene KD

• cDNA Overexpression

• In Vitro and In Vivo Target Validation/POC

• Lentivirus & Stable Cell Line Generation

• Molecular Cloning

• Recombinant Protein Production

• In vitro Assay Development & Validation

• Compound Screening & Counter Screening

• SAR & MOA

• Target Engagement Assays

• Cell Signaling Assays

• Cell Functional Assays

• Protein Degradation Assays

• Primary Immune Cell Assays

• In vivo Pharmacology

• Oncology

• Immuno-oncology

• Autoimmune

• Inflammation

• Efficacy Studies

• PK/PD Correlation

• Biomarker/Translational Science

• IND Filing Support

Biologics Drug Discovery Solutions

• CRISPR Library Screen

• siRNA Gene KD

• shRNA Gene KD

• CRISPR/Cas9 Gene KO

• CRISPR/dCas9 Gene KD

• cDNA Overexpression

• In Vitro and In Vivo Target Validation/POC

• Plasmid construction

• Recombinant Protein Production

• Recombinant Antibody Production

• Recombinant Cell Line Generation

• Assay Development

• Hybridoma (collaboration)

• Phage Library & Phage Display (collaboration)

• Antibody Screening and Characterization

• Binding/Blocking Assays

• Functional Assays

• Physical Properties

• Antibody Engineering (collaboration)

• In vivo PK

• In vivo Efficacy/PKPD

• Oncology

• Immuno-oncology

• Autoimmune

• Inflammation

• Biomarker/Translational Science

• Development Support

Antibody & Protein Catalogue Solutions

Immunology Solutions

• PBMC/Blood Assays

• T-Cell Assays

• B/NK Cell Assays

• Monocyte Assays

• Large collection of species available

• Large selection of organs and other biologic specimens available

• Broad selection of technology platforms for analysis

• Selection of customizable readout types.

• T /Treg Cells

• B/NK Cells

• Monocytes/ Macrophages

• Dc/pDC

• MDSC

• Granulocytes

• HSC

• Plasma Cells

• p-CREB

• p-STAT3/p-STAT6

• PD-1/PD-L1

• Tim-3

• Lag-3

• CTLA-4

• TIGIT

• IFN-y

• IL 2/4/17A/10

• TNF-a

• CD 25/69/44/107a/83

In Vivo Pharmacology Solutions

• Subcutaneous / Systemic / Metastasis

• 26 Cancer types

• Total 200+ models

• Humanized immune system

• Subcutaneous / Systemic / Metastasis

• 9 Cancer types

• huGene K/I mice experience

• Combined immunotherapy

• Respiratory disease

• Rheumatoid Arthritis

• Experimental autoimmune encephalomyelitis

• Inflammatory Bowel Disease

• Skin-related Disease

• Systemic Inflamation

• Leukemia

• Lymphoma

• Liver Cancer

• Myeleoma

• Neuroblastoma

• Breast Cancer

• Glioblastoma

• Liver Cancer

• Lung Cancer

• Multiple Myeloma

• Ovarian Cancer

• Prostate Cancer

• Breast Cancer

• Lung Cancer

• Melanoma

• Prostate Cancer

DMPK Solutions

Our Services

Our mission at BioMetas is to provide our global clients with state of the art and innovative drug products, drug discovery, and development services.

Small Molecule Drug Discovery Solutions

• CRISPR Library Screen

• siRNA Gene KD

• shRNA Gene KD

• CRISPR/Cas9 Gene KO

• CRISPR/dCas9 Gene KD

• cDNA Overexpression

• In Vitro and In Vivo Target Validation/POC

• Lentivirus & Stable Cell Line Generation

• Molecular Cloning

• Recombinant Protein Production

• In vitro Assay Development & Validation

• Compound Screening & Counter Screening

• SAR & MOA

• Target Engagement Assays

• Cell Signaling Assays

• Cell Functional Assays

• Protein Degradation Assays

• Primary Immune Cell Assays

• In vivo Pharmacology

• Oncology

• Immuno-oncology

• Autoimmune

• Inflammation

• Efficacy Studies

• PK/PD Correlation

• Biomarker/Translational Science

• IND Filing Support

Biologics Drug Discovery Solutions

• CRISPR Library Screen

• siRNA Gene KD

• shRNA Gene KD

• CRISPR/Cas9 Gene KO

• CRISPR/dCas9 Gene KD

• cDNA Overexpression

• In Vitro and In Vivo Target Validation/POC

• Plasmid construction

• Recombinant Protein Production

• Recombinant Antibody Production

• Recombinant Cell Line Generation

• Assay Development

• Hybridoma (collaboration)

• Phage Library & Phage Display (collaboration)

• Antibody Screening and Characterization

• Binding/Blocking Assays

• Functional Assays

• Physical Properties

• Antibody Engineering (collaboration)

• In vivo PK

• In vivo Efficacy/PKPD

• Oncology

• Immuno-oncology

• Autoimmune

• Inflammation

• Biomarker/Translational Science

• Development Support

Antibody & Protein Catalogue Solutions

Immunology Solutions

• PBMC/Blood Assays

• T-Cell Assays

• B/NK Cell Assays

• Monocyte Assays

• Large collection of species available

• Large selection of organs and other biologic specimens available

• Broad selection of technology platforms for analysis

• Selection of customizable readout types.

• T /Treg Cells

• B/NK Cells

• Monocytes/ Macrophages

• Dc/pDC

• MDSC

• Granulocytes

• HSC

• Plasma Cells

• p-CREB

• p-STAT3/p-STAT6

• PD-1/PD-L1

• Tim-3

• Lag-3

• CTLA-4

• TIGIT

• IFN-y

• IL 2/4/17A/10

• TNF-a

• CD 25/69/44/107a/83

In Vivo Pharmacology Solutions

• Subcutaneous / Systemic / Metastasis

• 26 Cancer types

• Total 200+ models

• Humanized immune system

• Subcutaneous / Systemic / Metastasis

• 9 Cancer types

• huGene K/I mice experience

• Combined immunotherapy

• Respiratory disease

• Rheumatoid Arthritis

• Experimental autoimmune encephalomyelitis

• Inflammatory Bowel Disease

• Skin-related Disease

• Systemic Inflamation

• Leukemia

• Lymphoma

• Liver Cancer

• Myeleoma

• Neuroblastoma

• Breast Cancer

• Glioblastoma

• Liver Cancer

• Lung Cancer

• Multiple Myeloma

• Ovarian Cancer

• Prostate Cancer

• Breast Cancer

• Lung Cancer

• Melanoma

• Prostate Cancer