Immunology Services
In Vitro Assay Platform
- Highlights
- Broad coverage on cell type
- Multiple species available
- Off-the-shelf assay model
- Customized assay per needs
- Open to assay co-development
PBMC / Blood
- PBMC / tumor cell killing assay
- Cytotoxicity evaluation
- TLR-agonist induced cytokine release assay
- LPS induced cytokine release assay
- Cytokine storm evaluation
- JAK pathway selectivity
- Basophil activation assay
T cell
- T cell activation / proliferation assay
- T cell differentiation (Th1/2/17) assay
- Tumor cell co-culture assay
- Treg suppressive assay
- Mixed lymphocyte reaction (MLR)
- NECA-induced cytokine / cAMP / pCREB assay
- AMP-mediated cytokine release assay
B / NK cell
- B cell Activation assay
- NK cell activation assay
- NK cell killing assay
- NK cell proliferation assay
- ADCC assay
Monocyte
- Macrophage polarization assay
- Macrophage phagocytosis assay
- NLRP3 inflammasome activation assay
- Monocyte activation assay
- STING antagonist assay
- Highlights
- Experienced with multi-species
- Skilled on tissue processing
- Multi-color flow cytometry
- Cytokine measurement
- Transcriptome screening
Ex vivo PD Analysis Platform
Species
- Healthy donor
Human whole blood/PBMCs - Large animals
Cyno-Monkey, Dog - Rodents
Mouse, Rat
Sample Types
- Tumor/Spleen
- Lymph nodes
- Bone marrow
- Peripheral blood
- Plasma/Serum
- BALF/Peritoneal cells
- Tissue homogenate
Tech-Platforms
- Flow cytometry
- ELISA
- AlphaLISA
- ProQuantum
- Luminex
- QuantiGene
- scRNA seq(with partner)
Readout Types
- Flow cytometric analysis
- Cytokine profiling
- Phospho-Pr. measurement
- mRNA detection
- Transcriptome screening
Immune Cell Phenotyping
- T cells
- Treg
- B cells
- NK cells
- Monocytes
- Macrophages
- DCs
- pDC
- MDSC
- Granulocytes
- HSC
- Plasma cells
Biomarker Analysis
- p-CREB
- p-STAT3
- p-STAT6
- PD-1/PD-L1
- Tim-3
- Lag-3
- CTLA-4
- TIGIT
- IFN-γ
- IL-2
- IL-4
- IL-17A
- IL-10
- TNF-α
- Granzyme B
- Ki67
- CD25
- CD69
- CD44
- CD107a
- NKG2A
- CD83
In Vitro Assay Platform
- Highlights
- Broad coverage on cell type
- Multiple species available
- Off-the-shelf assay model
- Customized assay per needs
- Open to assay co-development
PBMC / Blood
- PBMC / tumor cell killing assay
- Cytotoxicity evaluation
- TLR-agonist induced cytokine release assay
- LPS induced cytokine release assay
- Cytokine storm evaluation
- JAK pathway selectivity
- Basophil activation assay
T cell
- T cell activation / proliferation assay
- T cell differentiation (Th1/2/17) assay
- Tumor cell co-culture assay
- Treg suppressive assay
- Mixed lymphocyte reaction (MLR)
- NECA-induced cytokine / cAMP / pCREB assay
- AMP-mediated cytokine release assay
B / NK cell
- B cell Activation assay
- NK cell activation assay
- NK cell killing assay
- NK cell proliferation assay
- ADCC assay
Monocyte
- Macrophage polarization assay
- Macrophage phagocytosis assay
- NLRP3 inflammasome activation assay
- Monocyte activation assay
- STING antagonist assay
Ex vivo PD Analysis Platform
- Highlights
- Experienced with multi-species
- Skilled on tissue processing
- Multi-color flow cytometry
- Cytokine measurement
- Transcriptome screening
Species
- Healthy donor
Human whole blood/PBMCs - Large animals
Cyno-Monkey, Dog - Rodents
Mouse, Rat
Sample Types
- Tumor/Spleen
- Lymph nodes
- Bone marrow
- Peripheral blood
- Plasma/Serum
- BALF/Peritoneal cells
- Tissue homogenate
Tech-Platforms
- Flow cytometry
- ELISA
- AlphaLISA
- ProQuantum
- Luminex
- QuantiGene
- scRNA seq(with partner)
Readout Types
- Flow cytometric analysis
- Cytokine profiling
- Phospho-Pr. measurement
- mRNA detection
- Transcriptome screening
Immune Cell Phenotyping
- T cells
- Treg
- B cells
- NK cells
- Monocytes
- Macrophages
- DCs
- pDC
- MDSC
- Granulocytes
- HSC
- Plasma cells
Biomarker Analysis
- p-CREB
- p-STAT3
- p-STAT6
- PD-1/PD-L1
- Tim-3
- Lag-3
- CTLA-4
- TIGIT
- IFN-γ
- IL-2
- IL-4
- IL-17A
- IL-10
- TNF-α
- Granzyme B
- Ki67
- CD25
- CD69
- CD44
- CD107a
- NKG2A
- CD83