RMP1-14-mIgG1
Introduction
RMP1-14 is specific clone name for a rat anti-mouse PD-1 (also known as CD279) antibody. The original hybridoma was generated by immunizing Sprague Dawley rats with mouse PD-1-transfected BHK cells. A P3U1 myeloma was used as the fusion partner. Similar to J43, another mAb to mouse PD-1, RMP1-14 blocks the binding of both B7-H1-Ig and B7-DC-Ig to PD-1 transfectants. It has been used extensively to probe the effects of PD-1 inhibition in preclinical murine models.
Size | 1mg, 5mg, 10mg, 50mg, 100mg |
Brand | BioMetas |
Product type | Biosimilar |
Clonality | Monoclonal Antibody |
Expression system | CHO Stable pool |
Applications | Elisa, assay, in vivo |
Product name | RMP1-14-mIgG1 |
Species | Mus musculus |
Expression system | CHO stable pool |
Buffer | PBS, pH 7.4 |
Delivery condition | Dry ice (-80°C) |
Delivery Time | 1 week if in stock; 4 weeks if production needed |
Storage condition | Store at -80°C |
Brand | BioMetas |
Applications | ELISA, assay, in vivo |
Aliases/Synonyms | |
Reference | |
Note | For research use only. Not suitable for clinical or therapeutic use. |
Isotype | mIgG1 |
Clonality | Monoclonal Antibody |
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Data Gallery
Fig. 1.) 4-20% SDS-PAGE analysis
Recombinant protein was visualized by Coomassie Brilliant Blue R250 staining.
Fig. 2.) SEC-HPLC analysis
Column: Superdex 200 Increase 5/150 GL Running buffer: 2xPBS, pH 7.4
Bioactivity
