Insect Cell
Expression Services
Biometas provides the high-quality recombinant protein expression services using our in-house baculovirus–insect cell system from gene synthesis to protein production. Compared with bacterial expression system, this platform supports improving protein solubility of intracellular and secreted proteins with complex post-translational modifications. In addition, its high protein expression levels compared to other higher eukaryotes system renders it an excellent choice for difficult-to-express proteins, including but not limited to cytotoxic proteins, larger proteins, protein complexes and membrane proteins. We highly recommend this cost-effective eukaryotic protein expression system for eukaryotic protein production. Combining our long-standing expertise in protein production and a complete platform, Biometas optimize all the steps and boost the yield of your insect cell expression.
- Highlights
- Long-standing expertise
- Wide variety of cell lines and expression vectors
- Codon optimization for insect cell expression
- Several optimization parameters: insect cell line, Virus titration, multiplicity of infection and incubation time
Production Process
Case Study
Protein kinases remain one of the most interesting targets for small molecule targeted drug discovery. High quality protein is fundamental to set up in vitro assays. Though most of kinases are commercially available, sometimes it’s cost-prohibitive especially when large amount protein is required for a specific study. Below is case study of producing a well-known kinase protein by baculovirus system. 10mg of target protein was produced in 6 weeks with desired purity and activity.